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PhysiCell: An open source physics-based cell simulator for 3-D multicellular systems

Fig 3

HDS growth.

Left: The deterministic and stochastic necrosis models both give approximately linear growth (left), but the HDS with deterministic necrosis model grows faster (∼ 5% difference in diameter at day 18). Right: The HDS with stochastic necrosis has fewer cells than the deterministic model (∼ 26% difference in cell count at day 18), due to its delay in necrosis. The difference in cell count is larger than the difference in tumor diameter because most of the difference lies in the number of necrotic cells, and necrotic cells are smaller than viable cells.

Fig 3