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Polarization and migration in the zebrafish posterior lateral line system

Fig 12

Dose response experiment using SU5402.

The FGF receptor blocker SU5402 increases the size of the WntR activity domain in a dose-dependent manner (lef1 used as a marker). The size of the lef1 domain has been normalized relative to the size of the whole PLLP. A Linear regression analysis resulted in y = 0.2005x + 0.515. A one-way ANOVA reveals that the slope is significantly non-zero (0.2005 ± 0.03012). The 95% confidence interval for the slope is 0.1405—0.2605, with R2 = 0.3536, and P < 0.0001. These results validate the findings of our model.

Fig 12