Mindboggling morphometry of human brains
Mindboggle’s thickinthehead algorithm estimates cortical thickness for each brain region without relying on cortical surface meshes by dividing the volume of a region by an estimate of its middle surface area. Clockwise from lower left: 3-D cross-section and sagittal, coronal, and axial slices. The colors represent the inner and outer “surfaces” of cortex created by eroding gray matter bordering white matter and eroding gray matter bordering the outside of the brain. The middle surface area is estimated by taking the average volume of these inner and outer surfaces.