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Decoding Structural Properties of a Partially Unfolded Protein Substrate: En Route to Chaperone Binding

Fig 8

Non-native interactions.

A-C) Distribution of C-α distances of three crucial non-native interactions in I2: Val191-Leu151, His53-Tyr107, and His118-Leu114, as shown in blue, red, and magenta, respectively. The native protein distance distribution is shown in gray, where these non-native contacts are largely absent. D-E) Representative snapshots of the native and I2 displaying the corresponding residues in colored stick representation.

Fig 8