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Genome Modeling System: A Knowledge Management Platform for Genomics

Fig 1

Overview of the GMS.

The genome modeling system (GMS) is implemented to use a federated disk SAN, with meta-data stored in a PostgreSQL relational database. Sample management tools allow the import of new samples and instrument data. Data are then processed through various analysis pipelines (e.g., reference alignment, somatic variation detection, etc.) that in turn are managed and monitored by a workflow system (Box 1). Stand-alone GMS tools, not part of automated pipelines, are available through a common tool tree. Most components of the system can be accessed through an Ubuntu Linux command-line interface or Ruby-on-Rails web interface.

Fig 1