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Linear Motif-Mediated Interactions Have Contributed to the Evolution of Modularity in Complex Protein Interaction Networks

Figure 3

Enrichment of DLIs and DDIs in interactions between and within biological modules.

(a) Odd ratio in functional groups. (b) Two functional groups, ‘cell-cell adhesion’ and ‘leukocyte migration’ were shown. (c) Odd ratio in protein complexes. (d) Two protein complexes, ‘RNA polymerase II’ and ‘BRCA1-associated genome surveillance’ were shown. (e) Odd ratio in subcellular localizations. (f) Two subcellular localizations, ‘cytoplasm’ and ‘nucleus’, were shown.

Figure 3