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Substrate-Specific Reorganization of the Conformational Ensemble of CSK Implicates Novel Modes of Kinase Function

Figure 1

Small-angle X-ray scattering curves and Kratky plot of experimental data.

A) Solution scattering data for apo Csk (black), AMP-PNP bound Csk (red), and ADP bound Csk (blue). B) Kratky plot of experimental solution scattering data colored in the same manner as A. Scattering data is normalized for ease of comparison in the plot.

Figure 1