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Thousands of Rab GTPases for the Cell Biologist

Figure 1

Flowchart of the Rabifier.

(A) Identification- and (B) classification-procedure implemented by the Rabifier, see Results and Discussion for details on the two phases. Panel (C) shows descriptive statistics from the application of the Rabifier to 247 genomes in the Superfamily database, and details about Monosiga brevicollis. Abbreviations: best BLAST hit (BH) [37], Rab family motif (RabF) [24], reverse Ψ-BLAST (RPS-BLAST) [38], subfamily (sf.), Rab not classified to any subfamily within our internal reference set (RabX).

Figure 1