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Transat—A Method for Detecting the Conserved Helices of Functional RNA Structures, Including Transient, Pseudo-Knotted and Alternative Structures

Figure 4

Performance of Transat for detecting the known base-pairs (bp) and helices (helix) of the Rfam data set.

The top left figure shows the sensitivity as function of the false positive rate (FPR) and the top right figure the sensitivity (Sens) as function of the positive predictive value (PPV). The bottom left figure shows the F-measure and the bottom right figure the MCC as function of the p-value threshold, see the text for the definitions of the F-measure and the MCC. Note that each data point in the figures above corresponds to the respective performance measure averaged over the entire Rfam data set for a particular p-value threshold (along the x-axis).

Figure 4