On the Accessibility of Adaptive Phenotypes of a Bacterial Metabolic Network
Shown are the correlation length (CL) of phenotype differences, the normalized mutual information (NMI) of genotype differences relative to phenotype differences, and the number of essential genes (essentiality) found in the metabolic network, under different environmental conditions. The environments are listed in increasing order of quality, except in the case of lactose whose position in the rank-ordering is not known precisely. The NMI was computed as described in Materials and Methods, using a mutation rate per genotype position of 0.001. Error bars indicate 95% confidence intervals.