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Measuring Global Credibility with Application to Local Sequence Alignment

Figure 2

Histograms of the distances of the sampled alignments from the EC and MS.

In (A) the centroid and optimal alignments are similar and represent the distribution well, but in (B) and (C), despite a similar centroid and optimal alignment, neither represent the overall alignment distribution. In (D) it is observed that the centroid and optimal deviate significantly from each other, and that the centroid is a much better representation of the alignment space.

Figure 2