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A benchmark of semi-supervised scRNA-seq integration methods in real-world scenarios

Fig 2

Baseline settings: using unsupervised methods results.

(a) Bar plots showing the performance of all methods across six datasets under this setting. Each bar represents the overall weighted score of a method; triangles and circles indicate the batch correction and biological conservation scores, respectively. In each dataset sub-figure, the left panel displays the performance of five semi-supervised methods provided with full labels, represented by solid-colored bars. The right panel shows the performance of five unsupervised methods, depicted with empty (unfilled) bars. (b) Bubble plot of all the methods relative ranking considering the overall weighted score, bio conservation score and batch correction score. The first column of each color group represents the average performance of each method across all six datasets. (c) Scatter plot of the average overall batch correction score against the average overall bio conservation score for each methods across all datasets. The error bars represent the standard error of the mean for each method and score type across all datasets. The horizontal red dashed line represents the average bio conservation score across all methods, while the vertical blue dotted line represented the average batch correction score.

Fig 2

doi: https://doi.org/10.1371/journal.pcbi.1014008.g002