Impact of ligand binding on VEGFR1, VEGFR2, and NRP1 localization in human endothelial cells
Fig 6
Impact of VEGFR1 on whole cell VEGFR2 ligation by VEGF165a.
A, changes in VEGFR2.VEGF165a.VEGFR2 levels under varying VEGF165a concentrations B, changes in VEGFR2.VEGF165a.VEGFR2 in the absence of VEGFR1 levels under varying VEGF165a concentrations C, percent change in VEGFR2.VEGF165a.VEGFR2 levels under loss of VEGFR1 molecules and under varying VEGF165a concentrations. When VEGFR1 is removed, whole cell VEGFR2.VEGF165a.VEGFR2 levels change.