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Electrodiffusion dynamics in the cardiomyocyte dyad at nano-scale resolution using the Poisson-Nernst-Planck (PNP) equations

Fig 5

Formation of a Debye layer near a membrane in a PNP simulation.

We consider a simple 2D example with two ions. Initially, the concentrations are constant in and . The initial concentration of is 100 mM in both and , and the initial concentration of K+ is 100.1 mM in and 99.9 mM in . A: Ionic concentrations and charge density near the membrane as functions of x for five different points in time. B: Charge density, , 0.1 nm right of the membrane (x1) and 20 nm to the right of the membrane (x2) as functions of time. C: Illustration of the simulation setup. We use , ns and a uniform mesh with nm.

Fig 5

doi: https://doi.org/10.1371/journal.pcbi.1013149.g005