GABAergic neurons can facilitate the propagation of cortical spreading depolarization: experiments in mouse neocortical slices and a novel neural field computational model
Fig 5
(A) Space-time diagrams of the propagation of excitatory and inhibitory population potentials, the expansion of potassium concentration in space and time. (B) CSD propagation over the propagation axis Q. Top: Propagation in terms of average membrane potentials of the excitatory populations. Red horizontal line indicates the threshold detecting the wavefront of the propagating depolarization block. Middle: Propagation in terms of average membrane potentials of the inhibitory populations. Bottom: Expansion of the increasing potassium concentration towards the patch boundaries as the depolarization block propagates.