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Molecular dynamics study of differential effects of serotonin-2A-receptor (5-HT2AR) modulators

Table 1

Overview of the molecular dynamics (MD) simulations performed and the ligands used. Simulations are grouped as non-G-protein coupled (i.e., without the G protein construct; simulations 1–8) and G-protein-coupled (with the G protein construct; simulations 9–15). The PDB-template structures from which each simulation was initiated are also indicated and color-coded according to their inactive (blue) or active (red) receptor state.

Table 1

doi: https://doi.org/10.1371/journal.pcbi.1013000.t001