How synaptic strength, short-term plasticity, and input synchrony contribute to neuronal spike output
Fig 2
Excitatory synaptic connections formed with L2/3 neurons do not exhibit a systematic clustering of EPSP amplitude and short-term plasticity.
A Top, distribution of EPSP amplitudes recorded across all regular-spiking neurons (population distribution). Bottom, distributions of EPSP amplitudes measured across the 8 neurons, for which at least 5 synapses were found (cell distributions). N, number of synapses recorded per cell; p, non-parametric Kolmogorov-Smirnov test between each cell distribution and the population distribution, medians are indicated. Note that the synapses formed with the postsynaptic cell in any given experiment were removed from the respective population distribution that the cell was compared to. B Same analyses for short-term plasticity data, panel layout as in A; light green, facilitating synaptic connections; dark green, depressing connections, means are indicated. Note that the synapses formed with the postsynaptic cell in any given experiment were removed from the respective population distribution that the cell was compared to. C Estimation of the effect sizes that were detectible across the experimental series at the 5% significance level.