Mechanisms of hemoglobin cycling in anemia patients treated with erythropoiesis-stimulating agents
Fig 7
Transient cycling can be induced by events unrelated to treatment such as sudden blood loss.
(A–C) Simulated bleeding scenarios where hemoglobin levels have been instantly reduced by 4 g/dL at 12 months (gray arrow). Parameter values for the reference scenario (panel A) are provided in Table 1. Parameter changes in panels B and C as indicated in the plot. All display conventions as in Fig 3.