Deriving time-concordant event cascades from gene expression data: A case study for Drug-Induced Liver Injury (DILI)
Fig 5
|logFC| before adverse histopathology. For known processes in DILI which correspond to significantly enriched events before adverse histopathology, the max |logFC| before adverse histopathology is shown. In comparison to other known pathways and the overall background distribution, a high logFC is found for mitochondrial beta oxidation followed by peroxisomal beta oxidation and mitophagy.