Calcium modeling of spine apparatus-containing human dendritic spines demonstrates an “all-or-nothing” communication switch between the spine head and dendrite
Fig 8
“All or-nothing” spine-to-dendrite calcium communication.
Schematic illustration summarizing our major findings. Ca2+ communication between spine head and dendrite is controlled by the interplay between RyR density, and morphological changes of dendritic spines and spine apparatus organelles (SA) in the neck region. RyR, ryanodine receptors.