AI reveals insights into link between CD33 and cognitive impairment in Alzheimer’s Disease
Fig 2
Network representation of iVAMBN model for ROSMAP data.
Shown are the learned (grey) and knowledge-derived (green) edges between gene modules (purple nodes), single gene modules (green) and CD33 and phenotype module (red). All these edges appeared with bootstrap frequency > 0.4. The newly inferred shortest path between CD33 and phenotype is displayed in orange. Other edges with bootstrap frequency > 0.4 have been removed for visualization purposes, except for those six edges which were trained with a bootstrap confidence of 1.