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Autocrine signaling can explain the emergence of Allee effects in cancer cell populations

Fig 4

The population density after 11 days as a function of the death rate μ.

Results from the IB-model (circles) and the numerical solution of (3) (solid line) under (A) short range dispersal and no cell migration and (B) short range dispersal and a cellular diffusion coefficient of Dc = 1.6 × 10−10 cm2/s. All other parameter values are given in Table 1.

Fig 4

doi: https://doi.org/10.1371/journal.pcbi.1009844.g004