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Data-driven multi-scale mathematical modeling of SARS-CoV-2 infection reveals heterogeneity among COVID-19 patients

Fig 6

Bifurcation of parameter K4 and ρ for RIC, [Cytokines] and [Teffector] on day 30 after infection.

a-c for parameter K4 when the value of ρ is taken as 0.0025. d-f for parameter ρ when the value of K4 is taken as 84. Red solid circles and blue squares represent severe and mild-moderate cases, respectively. The other parameters are default and are shown in Table A in S1 Text. The gray region indicates a bistable status for mild-moderate and severe cases.

Fig 6

doi: https://doi.org/10.1371/journal.pcbi.1009587.g006