Towards integration of time-resolved confocal microscopy of a 3D in vitro microfluidic platform with a hybrid multiscale model of tumor angiogenesis
Fig 2
Schematic of microfluidic platform.
Fig 2A depicts the housing of the 3D microfluidic platform. The black oval denotes the boundary of the platform containing collagen matrix (shown in light pink) within the housing chamber. The chamber is connected to a syringe pump flow system, shown in Fig 2B, to maintain continuous flow of media through the parent vessel, within the collagen matrix. The axial cross-section of the vessel (the x-z plane) is shown in Fig 2C and an example z-slice image (i.e., longitudinal cross-section along the length of the vessel (the x-y plane)), is shown in Fig 2D.