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Tumor cell intrinsic and extrinsic features predict prognosis in estrogen receptor positive breast cancer

Fig 5

Individual signature and immune infiltration scores can identify prognostic patient groups.

Signature and immune infiltration scores fitted in a univariate Cox proportional hazards model without clinical adjustment (a) and with clinical adjustment (b) are associated with survival time. Patients are significantly dichotomized by their TP53_mut (c), TNFRSF17_amp (d), and MemB (e) score. f Risk groups dichotomized by the median Onco-score have lower or comparable significance to some of our signature and immune infiltration scores.

Fig 5

doi: https://doi.org/10.1371/journal.pcbi.1009495.g005