Modelling conformational state dynamics and its role on infection for SARS-CoV-2 Spike protein variants
Fig 3
Dynamical Signature clustering for the closed (A) and open (B) state structures for WT and 22 mutants from GISAID (S1 Table). The clustering measures the distance between each pair of Dynamical Signature. Different colors were used to identify branches within a threshold of similarity (8.7 and 3.2 for closed and open state, respectively). The branches that comprehend most strains containing the D614G mutation are highlighted in red.