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The evolutionary history of topological variations in the CPA/AT transporters

Fig 8

Fold-types and their evolution in CPA/AT transporters.

The four fold-types of CPA/AT transporters are shown. Topologies, type of core helix (Broken/reentrant), the orientation of the N-terminal helix as well as other data are listed. All the evolutionary events responsible for the evolution of fold-types are summarized. The TM helices (in-out) and TM helices (out-in) are colored dark grey and white, respectively. Reentrant helices (in-in) and (out-out) are colored yellow and blue respectively.

Fig 8

doi: https://doi.org/10.1371/journal.pcbi.1009278.g008