The evolutionary history of topological variations in the CPA/AT transporters
Fig 3
Visualization of the relationship between the families by a network linking families with significant similarities in the MSA-MSA alignments (E-value < 0.1 thin edges, E-value <0.001 thick edges) for repeat units (right) and full-length families (left). Each family/repeat is colored according to the fold type, Magenta: BART-fold, Green: CPA-reentrant, Red: CPA-broken and Blue: reentrant-helix-reentrant fold type. In the repeat unit network, a) N-terminal units are circular and C-terminal units are star-shaped. In the full protein network. b) The full proteins are square.