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Basis profile curve identification to understand electrical stimulation effects in human brain networks

Fig 2

Single-pulse cortico-cortical evoked potentials.

A: An array of brain surface (ECoG) electrodes were surgically placed on the left hemisphere of a brain tumor patient. B: The voltage (red trace) was measured at a parahippocampal gyrus (PHG) electrode site. C: Biphasic stimulation pulses were delivered between adjacent electrodes throughout the array (gray shows all stimulation pulse trials for stimulation at each site, red shows average). D: Responses from each stimulation pulse are aligned into a matrix Vk(t). E: Averaged subgroup responses Gn(t) (i.e. CCEPs, from the PHG measurement site) are shown between the two electrode sites that were stimulated to produce them.

Fig 2

doi: https://doi.org/10.1371/journal.pcbi.1008710.g002