Four different mechanisms for switching cell polarity
Fig 7
Behavior of the model at different noise levels.
A Switching probability as a function of noise strength for different switching mechanisms. Signal parameters are indicated by the corresponding symbols in Figs 3 and 4. Each data point represents the results of 104 stochastic realizations. B Probability of different numbers n of switching events at different noise levels for the prime-release switch. Signal parameters are as for Fig 4B. C States of 200 stochastic realizations (N = 104) of the prime-release switch at t = τ. Dashed line shows an estimate of the position of the separatrix in the absence of the signal (see ‘Methods’). D States of 200 realizations of the relaxation oscillator at t = τ (N = 104). Dotted line shows the deterministic limit cycle of the system during the signal, dashed lines indicate where the limit cycle intersects with the separatrix in the absence of signal. The three different panels in C and D show different two-dimensional projections of the nine dimensional phase space. Point type and color indicate whether the system switches polarity (red) or not (black).