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A mesoscopic simulator to uncover heterogeneity and evolutionary dynamics in tumors

Fig 8

Prognostic measures obtained from the mathematical model recapitulate the behavior of those obtained from MRI and PET images of GBMs.

A). Kaplan-Meier curves for the population splitting using the spherical rim width taking a threshold equal to 1.93 mm. Median survival difference between groups was 0.62 months. B). Kaplan-Meier curves for the population splitting using the surface regularity taking a threshold equal to 0.84. Median survival difference between groups was 0.58 months.

Fig 8

doi: https://doi.org/10.1371/journal.pcbi.1008266.g008