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Likelihood-free nested sampling for parameter inference of biochemical reaction networks
Fig 2
Illustration of likelihood approximation with a particle filter.
A: Top: Likelihood for different parameters k (red) and contour lines of the joint distribution Π(k, log(k) of the parameter k and its likelihood approximation 
, based on 106 samples of the likelihood approximation obtained with a particle filter with 100 particles. Bottom: The constrained priors π(k|l(k) > ϵ) and 
for ϵ = 1e − 24. B: Example distributions 
(blue) for k = 1, 1.2 and 1.4 and the true likelihood l(k) red.
doi: https://doi.org/10.1371/journal.pcbi.1008264.g002