Vector genetics, insecticide resistance and gene drives: An agent-based modeling approach to evaluate malaria transmission and elimination
Fig 4
Example of how traits and alleles interact in the vector genetics model.
There is no seasonal variation and no spatial component. (A) Genomes of mosquitoes in the model. Mosquitoes homozygous in ‘a0’ are the wild-type mosquitoes. Male mosquitoes carrying the ‘a1’ allele in a homozygous or heterozygous configuration have decreased mortality, which is thus a dominant trait, and is modeled as a halving of their probability of dying. (B) Distributions of genomes in the population over time average over 50 stochastic realizations. Male mosquitoes homozygous in the ‘a1’ allele are released mid-year during the first year of the simulation.