Combining hypoxia-activated prodrugs and radiotherapy in silico: Impact of treatment scheduling and the intra-tumoural oxygen landscape
Fig 3
Proliferative and slow-cycling or non-proliferative cells.
Top: Images from in vitro experiments performed by Voissiere et al. [35], in which cell nuclei are stained blue and proliferative cells are stained green by the proliferation marker Ki-67. Bottom: Images from in silico experiments performed in this study, where proliferative (cycling) cells are coloured green and inner (slow-cycling or non-proliferative) cells are coloured blue.