AlbaTraDIS: Comparative analysis of large datasets from parallel transposon mutagenesis experiments
Fig 4
The top 4 panels show the transposon insertion sites, 2 for libraries grown in 0.5 mg/L Triclosan and 2 controls.
The next panel shows the signal identified by AlbaTraDIS with the height corresponding to the log fold change between the treatments and controls. There is an increase in insertions in the promotor area (upstream) in the direction towards the gene, which indicates that up-regulation of fabI in E. coli grown in 0.5 mg/L of Triclosan might be beneficial to survival. This shows that AlbaTraDIS can identify the transposon insertions that alter expression of an essential gene.