FilterDCA: Interpretable supervised contact prediction using inter-domain coevolution
Fig 8
Fraction of true residue as a function of the FilterDCA score.
The fraction of true contacts is evaluated in the test sets for large (panel A) and medium (panel B) MSA sizes, as a function of the predicted contact probability P(⊕|x) provided by FilterDCA (filter size 45 × 45). We observe a clear linear relationship, with a slope slightly below one due to overfitting effects resulting from the finite training set and the limited complexity of our regression model.