Identifying determinants of persistent MRSA bacteremia using mathematical modeling
Fig 4
Comparison of models between resolving and persistent bacteremia.
(A, B) Line plots of the number of total, normal, and persister SA over time (0–60 days) for resolving (RB) and persistent bacteremia (PB). The detection limit of bacteremia was set as 0.1 cfu/a.u. and 2,479 and 2,135 models were classified into RB and PB, respectively. In RB, 52 of models showed relapsing bacteremia and they were also included in the analysis. (C) Two-dimensional scatter plot of switching rates. (D) Violin plots and box plots of the parameter distributions of RB and PB. Dotted lines indicate the range of randomized parameter values.