A multi-scale model of gas transport in the lung to study heterogeneous lung ventilation during the multiple-breath washout test
Fig 10
Measurements and simulation of N2MBW in healthy controls.
Simulated N2 washout compared to data from N2MBW tests from four healthy subjects (measurements (a)—(d)). For the simulations, the inlet flow profile and the FRC as measured during the N2 washout test were used. To match the washout envelope in the measured data, both lobular residual volume and lobular compliance were partially modified in the lung model to mimic normal lung heterogeneity.