Augmenting subnetwork inference with information extracted from the scientific literature
Fig 4
Overview of the HIV host-virus subnetwork inference task.
The first panel displays a background network composed of source RNAi hits (black), interface nodes (green), and interactions (dashed and solid lines). Each interface is connected to a target viral component (blue). We can optionally augment the set of sources by using genes identified by GADGET as being relevant to HIV replication (red outline). The second panel displays an inferred subnetwork. Elements of the background network that are not included in the inferred subnetwork are shown in light grey.