A multiscale modelling approach to assess the impact of metabolic zonation and microperfusion on the hepatic carbohydrate metabolism
Fig 5
Effect of sinusoidal length on STU functionality.
Sinusoidal length was 375 μm /300 μm/ 225 μm corresponding to 25/20/15 hepatocytes. Portal plasma glucose concentrations were 10 mM (red lines), 7 mM (green lines) and 4 mM (blue lines) corresponding to fed, normal and fasted state.