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Elucidation of molecular kinetic schemes from macroscopic traces using system identification

Fig 2

Second-order canonical configurations.

(A) Example of two first-order processes, a and b, described by first-order transfer functions Ga(s) and Gb(s) with parameters τa = 5 ms and ka = -1, and τb = 100 ms and kb = 1, and their responses in time (outputs ya(t) and yb(t)) to an ideal step input at t = 30 ms (u(t)). (B) Block diagram (left) and corresponding output y(t) (right) in response to a step input u(t) of the first-order processes Ga(s) and Gb(s) combined following the three canonical configurations: cascade, feedback and parallel.

Fig 2

doi: https://doi.org/10.1371/journal.pcbi.1005376.g002