Dynamic Nucleosome Movement Provides Structural Information of Topological Chromatin Domains in Living Human Cells
Fig 3
Structural information of CDs provided by single-nucleosome dynamics.
(A) The fractal dimension df within the nuclear interior region (β = 0.44) and the periphery region (β = 0.39) for α, according to Eq 16. (B) df and the size 〈R〉CD of CDs, and (C) df and the relaxation time τdf,α of nucleosomes in CDs within the nuclear interior region (colored circle) and the periphery region (colored square) calculated for various α values, according to Eqs 16, 17 and 18. (D) 〈R〉CD and the τdf,α within the nuclear interior region (colored circle) and the periphery region (colored square) calculated for α = 0.9 and various 〈N〉CD values, corresponding to the range of 200 kb to 4 Mb, according to Eqs 17 and 18.