Model-Based Evaluation of Spontaneous Tumor Regression in Pilocytic Astrocytoma
Fig 5
Non-existence of an EOR threshold in PA.
The derived PA-regression-function (purple line) allows to quantitatively predict the regression probability based on the critical tumor size estimated as 9 cm3, see also Table 1. Roughly, one cm3 of resected tumor mass will elevate the chance of regression by 10%. The direct consequence is the non-existence of an EOR threshold implying that any proportion of resected tumor mass will improve prognosis. This stands in contrast to the behavior of the regression function for a fictive high value of the risk coefficient of e.g. γ = 50 (black line).