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Timing and Variability of Galactose Metabolic Gene Activation Depend on the Rate of Environmental Change

Fig 7

Results of the mathematical model.

A) Simulated standard deviation of the accumulation time as a function of the depletion time for the full model (red dots) and a model lacking the energy scaling (blue dashed line). Note that the energy scaling recreates the non-monotonicity observed in the experiments. B) Box plots of the distributions of the different types of cell cycle lengths for the 3 hr depletion scheme. The red box plots are the experimental data, whereas the blue box plots are obtained from a simulation of Eq. (5). The distribution of the energy availability in the diauxic phase (ϵ) is obtained by fitting the model to the diauxic cell cycle data.

Fig 7

doi: https://doi.org/10.1371/journal.pcbi.1004399.g007