< Back to Article

A Reaction-Diffusion Model of Cholinergic Retinal Waves

Figure 2

Model produces realistic cholinergic waves.

A. Network dynamics showing spatiotemporal patterns of retinal waves B. Distribution of wave sizes, speeds, durations and inter-wave intervals from 2500 s of simulation. Mean wave size is 0.017 mm(0.059 mm), mean wave speed is 0.11 mm/s (0.022 mm/s), mean wave duration is 0.63 s (0.90 s), and mean inter-wave interval is 49 s (25 s). C. SACs exhibit variable participation in waves. Pearson correlation coefficient between a cell in the center of the domain and all other cells. The correlation coefficient for each variable is plotted as a function of euclidean distance between cells. Computed using one 2500 s simulation, with activity recorded every 0.1 s. Solid curve represents a loess moving average estimate of mean correlation as a function of distance. Shaded region highlights all points within one standard deviation of this mean curve.

doi: https://doi.org/10.1371/journal.pcbi.1003953.g002