Unveiling Time in Dose-Response Models to Infer Host Susceptibility to Pathogens
Figure 5
Dose-response curves and susceptibility distributions inferred from survival curves.
A, Curves represent the estimated dose-response relationships from fitting the model described in Methods to survival over time, for Wolb− (black) and Wolb+ (blue). Shaded areas represent the 95% CI. B, Distribution of susceptibility to infection in Wolb+. The posterior median distribution is the curve and the shaded area is the 95% CI. C, Posterior samples of the Beta-distribution shape parameters describing Wolb+ susceptibility in blue. Red dot marks the median of distribution.