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Amino Acid Changes in Disease-Associated Variants Differ Radically from Variants Observed in the 1000 Genomes Project Dataset

Figure 10

Dependence of mutation rates on the change in CpG status.

Rates of change from codons were calculated similarly to the amino acid rate matrix [36], but on a 61 by 61 codon matrix.

doi: https://doi.org/10.1371/journal.pcbi.1003382.g010