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Connecting the Kinetics and Energy Landscape of tRNA Translocation on the Ribosome

Figure 1

Energy landscapes.

Short length-scale diffusion on a rough landscape (bottom) may be averaged, yielding an effective diffusion , which is obtained from simulation. Effective diffusion leads to barrier crossing attempts, where the probability of crossing is governed by the height of the long length-scale barrier ().

doi: https://doi.org/10.1371/journal.pcbi.1003003.g001