Task-Dependent Changes in Cross-Level Coupling between Single Neurons and Oscillatory Activity in Multiscale Networks
Figure 1
The Manual Control (MC) and Brain Control (BC) tasks.
A) Schematic of the MC task, where monkeys use their right arm to perform a delayed center-out reaching task to move an on-screen cursor from a center cue to one of 8 peripheral targets. B) Schematic of the BC task, where monkeys use changes in the firing rates of a subset of recorded cells in order to move a cursor from the center to one of 8 targets (irrespective of physical movement). C) Timing of different trial sub-stages in the MC and BC tasks. Trials start with the appearance of central cue. A hold period (MC: 500 ms; BC: 100 ms) begins once the cursor enters the central cue. Upcoming target appears onscreen once cursor enters center. Go cue (central cue color change) indicates that monkeys can move the cursor to the designated target (via hand movement in MC or firing rate changes in BC), with a range of movement times. Holding the cursor within the target (MC: 400 ms; BC: 50 ms) triggers juice reward (500 ms), followed by the start of the next trial.