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Adaptive Temperature Compensation in Circadian Oscillations

Figure 3

Evolution of adaptive temperature compensation.

(A) Sketch of the initial adaptive topology and its subsequent network evolution. Parameters and equations are given in Supplementary Text S1. Properties of this network are further detailed in Figure 4. The input, which models the temperature; the output which adapts; and (Eqs 10 11) changes substantially with a temperature step and functions as a buffer are color coded. (B) Temporal behaviour of the evolved network for two different input trajectories (the colors follow (A)). The input oscillates, undergoes a random phase shift around time , and decays exponentially to a constant value. Note only the mean of the buffer changes substantially with the terminal input value.

doi: https://doi.org/10.1371/journal.pcbi.1002585.g003